The Longshanks mouse

In 2010, we began selectively breeding a common lab mouse stock, called CD1, for increases in tibia length relative to body mass. Six years later (~20 generations), we established the Longshanks mouse, which has ~15% longer tibiae, but the same body mass as random-bred CD1 mice. With this unique mouse, we have begun to unpack the "black box" of skeletal microevolution, from genomes to phenomes.

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Projects

genomics of microevolution

micro-evo-devo

phenotypic (co)evolution

function and performance